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An innovative solution to quantify
cerebrovascular system using a new biomarker



What data

Can we get from cerebral arteries?

What if there is a method to measure cerebral arterial 

Wall Shear Stress from TOF MRA?

Based on TOF MRA

Quick, Precise, and Noninvasive

Measurement of wall shear stress produced by

cerebral arterial blood as a new cerebrovascular biomarker


VINT offers you quantitative

Imaging data of arterise

An innovative solution to measuring and visualizing cerebral artery wall shear stress concurrently

Provision of SIG as a new cerebral artery biomarker, quicker and easier than conventional methods

Facillitated patient-physician commnuication from data visualization and report


  • Signal Intensity Gradient (SIG) is a biomarker that functions beyond a simple factor for diagnosis.

        It can help identify the cause and aid in prevention of various cerebrovascular disease.

  • SIG, as a surrogate marker, is highly correlated with wall shear stress, the tangential force of the

       flowing blood on the endothelial surface of the blood vessel.


To learn more about SIG, click below

Direct Assessment of Wall Shear Stress by Signal Intensity Gradient from Time-of-Flight Magnetic Resonance Angiography

Kap-Soo Han, Sang Hyuk Lee, Han Uk Ryu, Se-Hyoung Park, Gyung-Ho Chung, Young I Cho, Seul-Ki Jeong.

Impact of Endothelial Shear Stress on the Bilateral Progression of Unilateral Moyamoya Disease

Woo-Jin Lee, Seul-Ki Jeong, Kap-Soo Han, Sang Hyuk Lee, Young Jin Ryu, Chul-Ho Sohn and Keun-Hwa Jung

Association of Carotid Artery Endothelial Signal Intensity Gradient with Unilateral Large Artery Ischemic Stroke

Chan-Hyuk Lee, Sang Hyuk Lee, Young I Cho, Seul-Ki Jeong.

Comparison of Hemodynamic Visualization in Cerebral Arteries: Can Magnetic Resonance Imaging Replace Computational Fluid Dynamics?

Minh Tri Ngo, Ui Yun Lee, Hojin Ha, Ning Jin, Gyung Ho Chung, Yeong Gon Kwak, Jinmu Jung, Hyo Sung Kwak

How VINT Works?

  • Automatic segmentation and 3D artery reconstruction 
    when the DICOM files are imported

  • Selection and labeling of region(s) of interest on the 3D model.

  • Provision of a report for effective communication with patient

VINT  allows for a quick instrumentation of SIG
through a simple process without any additional setups

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